Blue Sky specializes in baculoviral services.  Contact us now to get more information about our baculoviral services.

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Insect cells are the preferred module for high-level recombinant protein expression of many disease-relevant protein families. Several popular kit systems exist in the protein expression marketplace, however all common systems utilize baculovirus as a vector for host infection and protein production.

The most challenging element of baculoviral-mediated (baculo) protein expression is low batch-to-batch (lab-to-lab) replicability. Blue Sky has developed a multi-component system which employs Infection Kinetics Monitoring (IKM) technology. This system compiles a suite of real-time cell population measurements, read during the course of viral infection.

In tandem with standard scouting measures (such as Western Blot), IKM substantially decreases the guesswork associated with scale-up baculo expression. This system also obviates the need for laborious baculoviral titration. IKM makes baculo expression more predictable.

Get more general baculovirus expression information