The insulin receptor (InR) is a transmembrane receptor that is activated by insulin. It belongs to the large class of tyrosine kinase receptors. Insulin binds to its receptor which in turn starts many protein activation cascades. These include: translocation of Glut-4 transporter to the plasma membrane and influx of glucose, glycogen synthesis, glycolysis, and fatty acid synthesis.
This protein is homologous to amino acid residues R980 to S1382 of published Insulin receptor [Homo sapiens] NP_000199. It also has an 8-His-TEV tag on the N terminus.
InR TDA 2.0 kits
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