Fatty acid synthase (FAS) is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA in the presence of NADPH into long-chain saturated fatty acids. FAS is up-regulated in breast cancers and, as well as being an indicator of poor prognosis, may also be worthwhile as a chemotherapeutic target. FAS has also been investigated as a possible oncogene.

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