Blue Sky BioProducts
SmartScreen - Biologically Relevant, Context Sensitive

What is SmartScreen?

SmartScreen kits are based on TDA 2.0™ technology, a synthetic vesicle composed of derivitized lipids which bind HIS-tagged proteins.  SmartScreen™ kits contain pre-validated high-quality enzyme, TDA 2.0, substrate and reaction buffers in a simple to use, HTS compatible format.

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Why SmartScreen?

TDA 2.0™ logoBlue Sky’s template-directed self-assembly (TDA 2.0™) technology, TDA 2.0™, replicates the biological context of a cellular membrane and enables the development of in vitro assays with more relevant biochemical activity, resulting in the identification of novel drugs.

SmartScreen FAQ | Learn about TDA 2.0

Available SmartScreen Kits

Our first kits contain intracellular domains of receptor tyrosine kinases, such as hormone and growth factor receptors. Here are some of the kits that are currently available for purchase:

  • IGF1R Kit - His-tagged IGF1R complete intracellular domain RTK enzyme, TDA 2.0™, reaction buffers, and substrate.
  • Insulin Receptor Kit - His-tagged insulin receptor complete intracellular domain RTK enzyme, TDA 2.0™, reaction buffers, and substrate.
  • Lyn Kinase Assay Kit - His-tagged Lyn complete intracellular domain enzyme, TDA 2.0™, reaction buffers, and substrate.

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TDA My Way

Don't see what you need on the site? Not a problem. Our team of scientists will collaboratively develop an assay to meet your requirements, including custom protein production and field application service in your laboratory, for maximum flexibility. We call it "TDA My Way".

TDA My Way Information

Additional Assay Solutions

Our intelligently designed kits are useful for assessing activity of disease-relevant enzymes and the discovery of agonists or antagonists. These assay components can easily be integrated into existing HTS campaigns and enable new approaches to your targets.

Additional Assay Solutions

Blue Sky BioProducts

Blue Sky BioProduct lines focus on key pathways of disease-reliance, such as growth factor signaling and fatty acid metabolism. We currently offer many assay validated enzymes for high-throughput screening, selectivity analysis, and crystallography.

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Metabolic Syndrome

Metabolic SyndromeThe diseases which contribute to metabolic syndrome, such as diabetes, obesity and atherosclerosis, represent a major research discipline. Browse our reagents designed to facilitate research and expedite drug discovery related to these pathologies.

Metabolic Syndrome Products

Immunology

ImmunologyCommon cytokines (such as TNF-alpha) and antigens (such as myelin oligodendrocyte glycoprotein, MOG, for induction of autoimmune disease) can be found in this category

Immunology Products

Research Tools

Research ToolsWe offer many utility enzymes commonly used in reasearch, such as proteases (TEV, TVMV) and other modifying enzymes.

Research Tools

BioProducts & BioServices

Synergy produces more flexibility, convenience and quality for our customers


Blue Sky BioProducts and BioServices work closely together, allowing us to rapidly and collaboratively develop the exact reagent your research requires.

BioProducts Downloads

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Contact the BioProducts Team

Blue Sky Biotech
60 Prescott Street
Worcester , Massachusetts , 01605-2661
(800) 383-7795

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